Steps have been provided below to disable Time Off booking related email notifications for the required user:-
1) Log in to Replicon as the Administrator. 2) Click on the Administrator tab 3) Click on the Users. 4) Locate the user for which the email notification requires to be disabled. 5) Edit the user profile. 6) Click on email notification and uncheck the notification 'Time off booking is waiting for approval' or other Time off notifications as required to be stopped for the user.
The above steps have been demonstrated in this video